The A1 is closed in both directions between the A46 and the B6326 near Newark-on-Trent, due to a serious accident involving two lorries, a van and several other vehicles.
Nottinghamshire Police are on scene and all emergency services are in attendance, including an air ambulance.
Northbound traffic is being diverted off the A1 onto the Beckingham Road eastbound towards Coddington.
At Coddington take the A17 northbound and re-join the A1 at the junction with the A46.
The southbound diversion is the reverse of the above.
Road users are advised to expect delays and to allow plenty of time for journeys this morning.