Ilkeston police station is one of 17 that will have new opening hours from Monday.
The changes have been made after cuts to the force’s budget.
The station, on Heanor Road, will now be open from 9am to 5pm Monday to Friday.
In January, the force proposed changes to the front counter service at stations across Derbyshire to best meet demand including closures at under-used locations and altered opening hours at others.
Assistant Chief Constable Dee Collins said: “We examined every single one of our enquiry offices and looked in detail at the services they provided and the number of visitors they received.
“It was clear that there was spare capacity across all sites and many of the smaller offices received a limited number of weekly visitors.
“The way we deliver services to the public has moved on greatly in the last few years and many of the things that enquiry offices used to be the first port of call for are being delivered elsewhere.
“This is not a decision we have taken lightly and I realise it is not going to be popular in some quarters but the fact of the matter is we have to make savings and deliver services that provide value for money.
“It was a difficult choice but we had to weigh up carefully between retaining buildings or retaining officers.”
For non-emergency matters call the police on 101.