Nutbrook travelled to bottom club Tutbury hoping for full points to push them up the league, but ended up falling to defeat.
Tutbury elected to bat first and lost their first wicket on 24 when Edgington was bowled by Danny Brooks for just one run.
Max Magann had Wesson caught by Andy Farmer for nought before a third wicket stand of 59 ended when McComb was bowled by Brooks for 11 to leave the hosts 88-3.
Opener Manek was still there on 65 and a fourth wicket stand of 36 was ended when Edwards was bowled by Steve Sanderson.
Wickets then fell quickly, Manek caught by Chris Palfreyman on the boundary off Rich Henshaw’s bowling for 88 and Tutbury eventually ending 158 all out, Henshaw ending with 4-20, Magann 3-34, Brooks 2-51 and Sanderson 1-17.
In reply, Nutbrook lost Brooks early on and were soon 33-4, but a fifth wicket stand of 45 between Henshaw and Magann aided things until Henshaw was out for 20.
Magann battled on as others fell around him before eventually being out for 49, as Nutbrook were all out just seven runs short of victory on 152, leaving a tough battle on for the remaining four games of the season.
Nutbrook second XI faced title chasers Belper CC.
Belper, batting first posted 165 all out thanks to a good bowling display by Nutbrook with Kev Flewitt (3-54) and skipper Mark Witham 5-18 ripping through the Belper card.
In reply, Nutbrook struggled with only Simon Taylor (21) and Craig Wilson (19) showing any resistance, Nutbrook eventually tumbling to 105 all out.
Nutbrook third XI, batting first against Mickleover, posted 244 , Alistair Hodgkinson with 47 and Rob Gilbert 55 amongst the runs.
Despite the efforts of Gary Whitehead 3-45, Mickleover reached the target to take the points.